You can activate all serums together but it depends upon your situation and medium of sending energy.
For example are you using these energies for one person? For one issue? In water ? Or directly by name or image?
As in water, you can put all these energies one by one and back to back but if there are other mediums like name or image or direct request to send energy then you can mention each energy for three times, one by one and send to the person.
In water, energies can be activated once in a day till consumed but all other mediums would require the request again or as needed.
If a critical case then energy request can be frequent but if it’s a regular healing then the request can be 4…5 times a day.
Similarly if there are different people and different mediums of sending energy then also you need to see what medium are you using for the person A and what energies and medium are you using for person B.